Gold nanostar-mediated neural activity control using plasmonic photothermal effects
Jee Woong Lee, Hyunjun Jung, Hui Hun Cho, Jung Heon Lee, Yoonkey Nam*
This work was led by Jee Woong in collaboration with Prof. Jung Heon Lee's lab (link) at Sungkyunkwan University. We used gold nanostar shaped nanoparticles to induce photothermal effects for neuromodulation. Unlike gold nanorods that are mainly used for phototheraml effects, our gold nano stars were synthesized by seedless methods under completely biocompatibile environment. We showed that gold nanostars were effective in inducing photothermal neural inhibition from single cell level to network level. HJ jung also contributed to this work with his DMD-based phototheraml patterning system for the single cell suppression experiment.
Source: Lee et al., Biomaterials 2018