In Vitro Microelectrode Array Technology and Neural Recordings
Yoonkey Nam & Bruce C. Wheeler
Critical Reviews in Biomedical Engineering, 2011
This is a review article on MEA recording technology. (link to article)
Retinal ganglion cell responses to voltage and current stimulation in wild-type and rd1 mouse retinas
Goo YS, Ye JH, Lee S, Nam Y, Ryu SB, Kim KH.
This work was mainly performed by Dr. YS Goo in Chung-book Univ. medical school. Seok-young Lee and Yoonkey Nam performed a series of experiments to measure and calculate currents while delivering voltage stimuli. NEL mainly contributed in producing Figure 2 in this paper.
충북대학교 의과대학 생리학교실 구용숙 교수님 연구실에서 진행한 망막 자극 연구에서 전압 자극에 따른 전류 및 전하밀도 측정 실험에 참여한 연구입니다
Combinatorial ALK/Smad and bFGF signals stimulate the differentiation of hESCs into the cardiac lineage
Yook JY, Kim MJ, Son MJ, Lee S, Nam Y, Han YM, Cho YS.
Seokyoung Lee and Y. Nam have been invited as co-authors of this work following the contribution in characterizating the electrophysiological properties of hESC derived cardiac tissues using our MEA system. The major work was done by Dr. Cho in KRIBB.
Link to article
Pitch-Dependent Acceleration of Neurite Outgrowth on Nanostructured Anodized Aluminum Oxide Substrates
by Dr. Woo Kyung Cho, Kyungtae Kang, Gyumin Kang, Min Jee Jang, Prof. Dr. Yoonkey Nam*, Prof. Dr. Insung S. Choi*
This work was a collaborative effort between NEL and Dr. Insung Choi's lab in Department of Chemistry. Anodized alumunum oxide substrates were applied to hippocampal neuronal culture system to study the effect of nano-textures on the neurite outgrowth. NEL members (Gyumin Kang did initial experiments with Dr. Cho and Kyungtae Kang and Min Jee Jang finished the experiment.) This work was published in high impact journal (impact factor 10.8 in 2008). (link)
Directional neurite growth using carbon nanotube patterned substrates as a biomimetic cue
This work was a collaborative work between Seoul National University (Hybrid Nano-Device and Nano-Assembly Lab, PI: Prof. S. Hong) and KAIST. CNT patterned substrates were fabricated at SNU and neurons were cultured and characterized at KAIST. We demonstrated that patterned CNTs were effective to guide neurite outgrowth at early developmental stage of dissociated rat hippocampal neurons.
Link to the article
Generation of Pattterned Neuronal Networks on Cell-Repellent Poly(oligo(ethylene glycol)Methacrylate) Films
by Kyung Tae Kang and Gyumin Kang
This work is a collaborative work with Prof. Insung Choi in Department of Chemistry. The idea was developed by Kyung Tae Kang and he worked with Gyumin Kang to prove the idea.
Link to article
Surface modified microelectrode array with flake nanostructure for neural recording and stimulation
Ju-Hyun Kim and Gyumin Kang
This was a collaborative work between Prof. Yang-Kyu Choi in EE department and NEL.
Prof. Nam initiated the idea of using the flake nanostrucutres (developed by Prof. Yang's lab) for the design of neuroelectronic interface and NEL performed electrode characterization, cell culture, and neural recording & stimulation. (link)
Inference of Combinatorial Neuronal Synchrony with Bayesian Networks
Jung S, Nam Y, Lee D.
Collaborative efforts on applying Bayesian networks on multichannel spike train has been accepted this month. This work was mainly performed by Dr. Sungwon Jung coadvised by Prof. Yoonkey Nam and Prof. Doheon Lee. (link)
Gyumin's manuscript on agarose microwell arrays has been published in Lab on a Chip journal.
This journal is one of the higly rated journals in BioMEMS field (2008 impact factor: 6.478)
G. Kang, J. Lee, C. Lee, Y. Nam, Agarose Microwell based Neuronal Micro-Circuit Arrays on Microelectrode Arrays for High Throughput Drug Testing, Lab Chip, DOI:10.1039/B910738J (link)
Systematic analysis of synchronized oscillatory neuronal networks reveals an enrichment for coupled direct and indirect feedback motifs
Dong CY, Lim J, Nam Y, Cho KH.
남윤기 교수가 투고한 '신경인터페이스 IC 기술 동향' 이 임베디드월드 9월호에 실렸습니다.
Direct rapid prototyping of PDMS from a photomask film for micropatterning of biomolecules and cells
H Hwang*, G Kang*, JH Yeon, Yoonkey Nam**, Je-Kyun Park**
Our first paper is accepted in Lab Chip.