(Google Scholar) (PubMed)
Book chapters
Y, Nam (2023) State-of-the-Art Technology on MEAs for Interfacing Live Neurons. In: Thakor N.V. (eds) Handbook of Neuroengineering. Springer, Singapore. (link)
H. Kang, Y. Nam*, "In Vitro Neural Recording by Microelectrode Arrays", book chapter in Stretchable Bioelectronics for Medical Devices and Systems, Rogers JA, Ghaffari R, and Kim DH (Eds), Springer. (link)
Review articles
Y. Nam and B. C. Wheeler, "In vitro microelectrode array technology and neural recordings," Crit Rev Biomed Eng, vol. 39, pp. 45-61, 2011. (link)
R. Kim, S. Joo, H. Jung, N. Hong, and Y. Nam*, "Recent trends in microelectrode array technology for in vitro neural interface platform," Biomedical Engineering Letters. 2014;4(2):129–141. (link)
N Hong, Y Nam*, "Neurons-on-a-Chip: In Vitro NeuroTools", Molecules and Cells. 2022 Feb 28;45(2). (link)
J.W. Lee, D. Kim, S. Yoo, H. Lee, G. Lee, Y. Nam*,"Emerging Neural Stimulation Technologies for Bladder Dysfunctions", Int. Neurourol Journal 2015;19:3-11. (Link)
Y. Nam. "Material considerations for in vitro neural interface technology", MRS Bulletin 2012;37:566-572. (Link)
Y. Nam, "Neuron-on-a-Chip technology: Microelectrode Array System and Neuronal Patterning, 뉴런온칩 기술: 미세전극칩시스템과 신경세포 패터닝 기술" J. Biomed. Eng. Res. 2009 Apr;30:103-112. [Korean 국문] (link)
남윤기, "Brain on a Chip 구현을 위한 MEA 기술의 현황과 전망", The Magazine of the IEEK, v.34 no.9 = no.280 , 2007, pp.35 - 43 [Korean, 국문] (link) (pdf)
Journal/Conference Proceedings Papers
2026
D. Yoon, Y. Nam, "Three-dimensional microelectrode arrays for in vitro neuronal network models: structural designs, manufacturing approaches, and future perspectives", Biomedical Engineering Letters. 2026 (in press) (link)
J Lee, D Yoon, J Lee, D Kim, E Kim, JH Yoon, HJ Kwon, S Chung, Y Nam*, H Kang*, "High-Spatiotemporal-Resolution Transparent Thermoelectric Temperature Sensor Arrays Reveal Temperature-Dependent Windows for Reversible Photothermal Neuromodulation", Advanced Functional Materials. 2026 Feb.;36:e16370 (link)
2025
D Yoon and Y Nam*, "Highly Customizable Scaffold-type 3D Microelectrode Array Platform for Design and Analysis of the 3D Neuronal Network in vitro", Advanced Functional Materials. 2025 Dec.; 35: e10446. (link)
S Kim, D Yoon, Y Choi, G Lee, Y Nam*, JK Park*, "Hybrid biofabrication of multilayered 3D neuronal networks with structural and functional interlayer connectivity", Biosensors and Bioelectronics. 2025 Nov.; 287:117688. (link)
2024
D Yoon and Y Nam*, "A 3D neuronal network read-out interface with high recording performance using a neuronal cluster patterning on a microelectrode array", Biosensors and Bioelectronics. 2024 Oct;261:116507. (link)
2023
N Hong and Y Nam*, "In vitro assays of neurite outgrowth and synapse formation using thermoplasmonic ablation technique", BioChip Journal. 2023 Sept.;17: 458–467 (link)
H Lee, GS Yi, Y Nam*, "Connectivity and network burst properties of in-vitro neuronal networks induced by a clustered structure with alginate hydrogel patterning", Biomedical Engineering Letters. 2023 Nov.;13:659-70. (link) (Matlab code)
2022
H Kang* and Y Nam, "The Effect of Electrostatic Force between the Nanoparticles and the Substrate on the Uniform Assembly of Inkjet-Printed Nanoparticles", J. Flex. Print. Electron. 2022; 1(1):79-89. (link)
A Andolfi, H Jang, S Martinoia, Y Nam*, "Thermoplasmonic Scaffold Design for the Modulation of Neural Activity in Three-dimensional Neuronal Cultures", BioChip Journal, 2022 Sep. 13. (link) (online full-text access) (Cover article)
H Jang, D Yoon, and Y Nam*, "Enhancement of Thermoplasmonic Neural Modulation Using a Gold Nanorod-Immobilized Polydopamine Film", ACS Applied Materials & Interfaces. 2022 May 19. (link)
HJ Jung, Y Nam*, "Optical recording of neural responses to gold-nanorod mediated photothermal neural inhibition", Journal of Neuroscience Methods, 2022 May 1;373:109564 (link)
N Hong, Y Nam*, "Neurons-on-a-Chip: In Vitro NeuroTools", Molecules and Cells. 2022 Feb 28;45(2). (link)
2021
Y An, Y Nam*, "Closed-loop control of neural spike rate of cultured neurons using a thermoplasmonics-based photothermal neural stimulation", Journal of Neural Engineering. 2021 Nov 12;18(6). (link)
A Lee, D Yoon, SY Han, H Hugonnet, WS Park, JK Park, Y Nam*, and YK Park*, "Label-free monitoring of 3D cortical neuronal growth in vitro using optical diffraction tomography", Biomedical Optical Express. 2021:12(11);pp. 6928-6939. (link)
HJ Kim, E Lee, M Nam, JK Chung, S Joo, Y Nam, W Sun*, "Contribution of Extracellular Matrix Component Landscapes in the Adult Subventricular Zone to the Positioning of Neural Stem/Progenitor Cells", Experimental Neurobiology. 2021 Aug 31;30(4):275-284. (link)
R. Kim and Y. Nam*, "Fabrication of a Nanoplasmonic Chip to Enhance Neuron Membrane Potential Imaging by Metal-Enhanced Fluorescence Effect ", BioChip Journal. 2021;15:171–178.(link) (online full-text access) (Cover article)
[Conf.Paper] Y An, Y Nam*, "Laser Power Determination Using Light-to-Heat Conversion Rate of Nanoplasmonic Substrates for Neural Stimulation," Annu Int Conf IEEE Eng Med Biol Soc. 2021 Nov;2021:6357-6360. (link)
[Conf. Paper] D Yoon, J Son, JK Park, Y Nam*. "Development of the micro-patterned 3D neuronal-hydrogel model using soft-lithography for study a 3D neural network on a microelectrode array". Annu Int Conf IEEE Eng Med Biol Soc. 2021 Nov;2021:1234-1237. (link)
2020
N. Hong and Y. Nam*, "Thermoplasmonic neural chip platform for in situ manipulation of neuronal connections in vitro", Nature Communications, 11, Article number: 6313 (2020) (link)
H. Kang, W. Hong, Y. An, S. Yoo, H. J. Kwon, Y. Nam*, "Thermo-Plasmonic Optical Fiber for Localized Neural Stimulation", ACS Nano 2020;14(9);11406-19. (link)
D.J. Kim, H. Kang, Y. Nam*, "Compact 256-channel multi-well microelectrode array system for in vitro neuropharmacology test", Lab Chip. 2020;20:3410-3422. (link)
Y. Ju, J.S. Park, D. Kim, B. Kim,J.H. Lee, Y. Nam, H.W. Yoo, B.H.Lee, Y.M.Han*,"SHP2 mutations induce precocious gliogenesis of Noonan syndrome-derived iPSCs during neural development in vitro", Stem Cell Res Ther. 2020 Jul 16;11(1):282. (link)
K. Kanders, H. Lee, N. Hong, Y. Nam, R. Stoop*,"Fingerprints of a second order critical line in developing neural networks", Communications Physics. 2020 Jan;3:13. (link)
2019
R. Kim and Y. Nam*,"Polydopamine-doped conductive polymer microelectrodes for neural recording and stimulation", Journal of Neuroscience Methods. 2019 Oct;326:108369. (link)
J.T. Oh, G.H. Lee, J. Rho, S. Shin, B.J. Lee*, Y. Nam*, Y.K. Park*, "Optical measurements of three-dimensional microscopic temperature distributions around gold nanorods excited by localized surface plasmon resonance", Physical Review Applied. 2019;11:044079. (link)
S. Joo and Y. Nam*, "Slow-wave recordings from micro-sized neural clusters using multi-well type microelectrode arrays", IEEE Trans. Biomedical Engineering. 2019 Feb;66(2):403-410. (link)
S. Yoo, JH Park*, Y. Nam*, "Single-Cell Photothermal Neuromodulation for Functional Mapping of Neural Networks" ACS Nano. 2019 Jan 22;13(1):544-551. (link)
J.R. Ryu, J.H. Kim, H.M. Cho, Y. Jo, B. Lee, S. Joo, U. Chae, Y. Nam, I.J. Cho, W. Sun*,"A monitoring system for axonal growth dynamics using micropatterns of permissive and Semaphorin 3F chemorepulsive signals", Lab Chip. 2019 Jan 15;19(2):291-305. (link)
2018
S. Joo, J. Lim, Y. Nam*, "Design and fabrication of miniaturized neuronal circuits on microelectrode arrays using agarose hydrogel micro-molding technique", BioChip Journal, 2018 Sept;12(3):193-201. (link)
S. Joo, SY Song, YS Nam, Y. Nam*, "Stimuli-responsive neuronal networking via removable alginate masks", Advanced Biosystems, 2018 Jul;2(7):1800030. (link)
J.W. Lee, H. Kang, Y. Nam*, "Thermo-plasmonic gold nanofilm for simple and mass-producible photothermal neural interfaces", Nanoscale, 2018 May 17;10(19):9226-9235. (link)
H. Jung, J. Kim, Y. Nam*, "Recovery of early neural spikes from stimulation electrodes using a DC-coupled low gain high resolution data acquisition system", Journal of Neuroscience Methods, 2018 Apr 27;304:118-125. (link)
H. Kang, G.H. Lee, H. Jung, J.W. Lee, Y. Nam*, "Inkjet-Printed Bio-Functional Thermo-Plasmonic Interfaces for Patterned Neuromodulation", ACS Nano 2018;12(2);1128-38. (link)
H. Kang, J.W. Lee, Y. Nam*, "Inkjet-printed multi-wavelength thermo-plasmonic images for anti-counterfeiting applications", ACS Applied Materials & Interfaces 2018;10(7);6764-71. (link)
J.W. Lee, H. Jung, H.H. Cho, J.H. Lee, Y. Nam*, "Gold nanostar-mediated neural activity control using plasmonic photothermal effects", Biomaterials. 2018 Jan;153:59-69. (link)
2017
H. Jung, H. Kang, Y. Nam*, "Digital Micromirror based Near-infrared Illumination System for Plasmonic Photothermal Neuromodulation", Biomedical Optics Express 2017;8(6):2866-78. (link)
H. Kang, J.Y. Kim, Y.K. Choi*, Y. Nam* "Feasibility Study of Extended-gate Type Silicon Nanowire Field-Effect
Transistors for Neural Recording", Sensors 2017;17(4):705. (link)N. Hong, S. Joo, Y. Nam*, "Characterization of axonal spikes in cultured neuronal networks using microelectrode arrays and micro channel devices", IEEE Trans. Biomed Eng 2017 Feb;64(2);492-98. (link)
[Conference Paper] D Berger, S. Joo, T. Lorimer, Y. Nam, R. Stoop*, :Power Laws in Neuronal Culture Activity from Limited Availability of a Shared Resource". In: Mantica G., Stoop R., Stramaglia S. (eds) Emergent Complexity from Nonlinearity, in Physics, Engineering and the Life Sciences. Springer Proceedings in Physics, vol 191. Springer, Cham. (link)
2016
M. J. Jang, W. R. Kim, S. Joo, J. R. Ryu, E. Lee, Y. Nam*, W. Sun*,"Cell-type dependent effect of surface-patterned microdot arrays on neuronal growth", Front. Neurosci. 2016 May 02; 10:217. (link)
J.R. Ryu, M. J. Jang, Y. Jo, S. Joo, D.H. Lee, B.Y. Lee, Y. Nam*, W. Sun*,"Synaptic compartmentalization by micropatterned masking of a surface adhesive cue in cultured neurons", Biomaterials 2016 March 19; 92:46-56. (link)
S Yoo, R Kim, JH Park*, Y Nam*, “Electro-optical Neural Platform Integrated with Nanoplasmonic Inhibition Interface”, ACS Nano 2016 Mar 09;10(4);4274-81. (Link)
K Kang, Y Park, M Park, MJ Jang, SM Kim, J Lee, JY Choi, DH Jung, YT Chang, MH Yoon*, JS Lee*, Y Nam*, and IS Choi*, "Axon-First Neuritogenesis on Vertical Nanowires", Nano Lett. 2016 Jan 13;16(1);675-80. (Link)
2015
S. Joo, J.Y. Kim, E. Lee, N. Hong, W. Sung, Y. Nam*, "Effects of ECM protein micropatterns on the migration and differentiation of adult neural stem cells", Scientific Reports. 2015 Aug 12;5:13043. (Link)
M.J. Jang and Y. Nam*, "NeuroCa: Integrated framework for systematic analysis of spatio-temporal neuronal activity patterns from large-scale optical recording data," Neurophotonics.2015 Jul;2(3):035003. (Link) (NeuroCa)
J. Joo, X. Liu, V. R. Kotamraju, E. Rouslahti, Y. Nam, and M. J. Sailor*, "Gated Luminescence Imaging of Silicon Nanoparticles", ACS Nano, 2015 Jun 23;9(6):6233-41. (Link)
S. Joo, K. Kang, Y. Nam*, "In vitro neurite guidance effects induced by polylysine pin-stripe micropatterns with polylysine background," J Biomed Mater Res A, 2015 Aug;103(8):2731-9. (Link)
M. J. Jang and Y. Nam*, "Agarose-assisted micro-contact printing for high-quality biomolecular micro-patterns," Macromolecular Bioscience, 2015 May;15(5):613-21. (Cover article) (Link)
R. Kim, Y. Nam*, "Electrochemical layer-by-layer approach to fabricate mechanically stable platinum black microelectrodes using a mussel-inspired polydopamine adhesive," J Neural Eng. 2015 Mar 4;12(2):026010. (Link)
K. Kang, S. Joo, J. Y. Choi, S. Geum, S. Hong, S. Lee,Y. H. Kim, S. Kim, M. Yoon, Y. Nam*, K. Lee*, H. Lee*, and I. S. Choi*, "Tissue-based metabolic labeling of polysialic acids in living primary hippocampal neurons," PNAS, 2015 Jan 20;112(3):E241-8. (Link)
2014
S. Yoo, S. Hong, Y. Choi, J. H. Park, and Y. Nam*, "Photothermal Inhibition of Neural Activity with Near-Infrared-Sensitive Nanotransducers," ACS Nano. 2014 Aug 26;8(8):8040-9.(Link)
D. Hong, K. Bae, S. Yoo, K. Kang, B. Jang, J. Kim, S. Kim, S. Jeon, Y. Nam, Y.G. Kim, I. S. Choi*, "Generation of cellular micropatterns on a single-layered graphene film," Macromol Biosci, vol. 14, pp. 314-9, Mar 2014.(Link)
K. Kang, S. Y. Yoon, S. E. Choi, M. H. Kim, M. Park, Y. Nam*, J.S. Lee*, I.S. Choi*, "Cytoskeletal Actin Dynamics are Involved in Pitch-Dependent Neurite Outgrowth on Bead Monolayers," Angew Chem Int Ed Engl. 2014 Jun 10;53(24):6075-9. (Link)
W. R. Kim, M. J. Jang, S. Joo, W. Sun*, and Y. Nam*, "Surface-printed microdot array chips for the quantification of axonal collateral branching of a single neuron in vitro," Lab Chip. 2014 Feb 21;14(4):799-805. (Link)
2013
Y. Moon, J. Y. Kim, W. R. Kim, H. J. Kim, M. J. Jang, Y. Nam, K. Kim, H. Kim, W. Sun, "Function of ezrin-radixin-moesin proteins in migration of subventricular zone-derived neuroblasts following traumatic brain injury," Stem Cells, vol. 31, pp. 1696-705, Aug 2013. (Link)
R. Kim, N. Hong, and Y. Nam, "Gold nanograin microelectrodes for neuroelectronic interfaces," Biotechnol J, vol. 8, pp. 206-14, Feb 2013. (Link)
2012
K. Kang, S. Lee, R. Kim, I. S. Choi*, and Y. Nam*, "Electrochemically driven, electrode-addressable formation of functionalized polydopamine films for neural interfaces," Angew Chem Int Ed Engl, vol. 51, pp. 13101-4, Dec 21 2012. (Link)
M. J. Jang and Y. Nam*, "Aqueous micro-contact printing of cell-adhesive biomolecules for patterning neuronal cell cultures", BioChip Journal, vol. 6, pp. 107-13, Jun 1 2012. (Link)
M. J. Jang and Y. Nam*, "Geometric effect of cell adhesive polygonal micropatterns on neuritogenesis and axon guidance," J Neural Eng, vol. 9, p. 046019, Aug 2012. (Link)
C. Y. Dong, D. Shin, S. Joo, Y. Nam, and K. H. Cho*, "Identification of feedback loops in neural networks based on multi-step Granger causality," Bioinformatics, vol. 28, pp. 2146-53, Aug 15 2012. (Link)
K. Kang, S. E. Choi, H. S. Jang, W. K. Cho, Y. Nam*, I. S. Choi*, J.S. Lee*, "In vitro developmental acceleration of hippocampal neurons on nanostructures of self-assembled silica beads in filopodium-size ranges," Angew Chem Int Ed Engl, vol. 51, pp. 2855-8, Mar 19 2012. (Link)
S. J. Yoo and Y. Nam*, "Neurons on Parafilm: versatile elastic substrates for neuronal cell cultures," J Neurosci Methods, vol. 204, pp. 28-34, Feb 15 2012. (Link)
2011
S. J. Yoo, J. Kim, C. S. Lee, and Y. Nam*, "Simple and novel three dimensional neuronal cell culture using a micro mesh scaffold," Exp Neurobiol, vol. 20, pp. 110-5, Jun 2011. (Link)
K. Kang, I. S. Choi*, and Y. Nam*, "A biofunctionalization scheme for neural interfaces using polydopamine polymer," Biomaterials, vol. 32, pp. 6374-80, Sep 2011. (Link)
S. Lee and Y. Nam*, " Automatic switching system for the impedance analysis of multichannel microelectrode arrays: limits and improvement scheme," J. Biomed. Eng. Res. 2011 Sept;32(3). [Korean]
Y. S. Goo, J. H. Ye, S. Lee, Y. Nam, S. B. Ryu, and K. H. Kim, "Retinal ganglion cell responses to voltage and current stimulation in wild-type and rd1 mouse retinas," J Neural Eng, vol. 8, p. 035003, Jun 2011. (Link)
Y. J. Oh, S. G. Park, M. H. Kang, J. H. Choi, Y. Nam, and K. H. Jeong, "Beyond the SERS: Raman enhancement of small molecules using nanofluidic channels with localized surface plasmon resonance," Small, vol. 7, pp. 184-8, Jan 17 2011. (Link)
J. Y. Yook, M. J. Kim, M. J. Son, S. Lee, Y. Nam, Y. M. Han, et al., "Combinatorial activin receptor-like kinase/Smad and basic fibroblast growth factor signals stimulate the differentiation of human embryonic stem cells into the cardiac lineage," Stem Cells Dev, vol. 20, pp. 1479-90, Sep 2011. (Link)
G. Goyal and Y. Nam*, "Neuronal micro-culture engineering by microchannel devices of cellular scale dimensions," Biomed. Eng. Lett. 2011;1(2):89 - 98. (Link)
2010
W. K. Cho, K. Kang, G. Kang, M. J. Jang, Y. Nam*, and I. S. Choi*, "Pitch-dependent acceleration of neurite outgrowth on nanostructured anodized aluminum oxide substrates," Angew Chem Int Ed Engl, vol. 49, pp. 10114-8, Dec 27 2010. (Link)
M. J. Jang, S. Namgung, S. Hong, and Y. Nam*, "Directional neurite growth using carbon nanotube patterned substrates as a biomimetic cue," Nanotechnology, vol. 21, p. 235102, Jun 11 2010. (Link)
K. Kang, G. Kang, B. S. Lee, I. S. Choi*, and Y. Nam*, "Generation of patterned neuronal networks on cell-repellant poly(oligo(ethylene glycol) methacrylate) films," Chem Asian J, vol. 5, pp. 1804-9, Aug 2 2010. (Link)
J. H. Kim, G. Kang, Y. Nam*, and Y. K. Choi*, "Surface-modified microelectrode array with flake nanostructure for neural recording and stimulation," Nanotechnology, vol. 21, p. 85303, Feb 26 2010. (Link)
S. Jung, Y. Nam*, and D. Lee*, "Inference of combinatorial neuronal synchrony with Bayesian networks," J Neurosci Methods, vol. 186, pp. 130-9, Jan 30 2010. (Link)
2009
G. Kang, J. H. Lee, C. S. Lee, and Y. Nam*, "Agarose microwell based neuronal micro-circuit arrays on microelectrode arrays for high throughput drug testing," Lab Chip, vol. 9, pp. 3236-42, Nov 21 2009. (Link)
C. Y. Dong, J. Lim, Y. Nam*, and K. H. Cho*, "Systematic analysis of synchronized oscillatory neuronal networks reveals an enrichment for coupled direct and indirect feedback motifs," Bioinformatics, vol. 25, pp. 1680-5, Jul 1 2009. (Link)
H. Hwang, G. Kang, J. H. Yeon, Y. Nam*, and J. K. Park*, "Direct rapid prototyping of PDMS from a photomask film for micropatterning of biomolecules and cells," Lab Chip, vol. 9, pp. 167-70, Jan 7 2009. (Link)
Y. Nam, E. A. Brown, J. D. Ross, R. A. Blum, B. C. Wheeler, and S. P. DeWeerth, "A retrofitted neural recording system with a novel stimulation IC to monitor early neural responses from a stimulating electrode," J Neurosci Methods, vol. 178, pp. 99-102, Mar 30 2009. (Link)
2008
E. A. Brown, J. D. Ross, R. A. Blum, Y. Nam, B. C. Wheeler, and S. P. Deweerth, "Stimulus-artifact elimination in a multi-electrode system," IEEE Trans Biomed Circuits Syst, vol. 2, pp. 10-21, Mar 2008. (Link)
2007
Y. Nam, G. J. Brewer, and B. C. Wheeler, "Development of astroglial cells in patterned neuronal cultures," J Biomater Sci Polym Ed, vol. 18, pp. 1091-100, 2007. (Link)
L. Rowe, M. Almasri, K. Lee, N. Fogleman, G. J. Brewer, Y. Nam, et al., "Active 3-D microscaffold system with fluid perfusion for culturing in vitro neuronal networks," Lab Chip, vol. 7, pp. 475-82, Apr 2007. (Link)